Article

Intracellular competitions reveal the combination of active partitioning and addiction mechanisms as most advantageous for low-copy plasmid fitness

2025-02-11

Abstract excerpt

Extrachromosomal and mobile genetic elements, including transposable elements, plasmids, and accessory chromosomes, are found across all domains of life. The replication and segregation of elements integrated into the host chromosome are ensured by the host life cycle. In contrast, the persistence of autonomously replicating elements relies on their ability to remain within the host population. Here, we compare th...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: e1769153-03fb-5f1b-8008-98137620e545
DOI: 10.1101/2025.02.11.637630

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Intracellular competitions reveal the combination of active partitioning and addiction mechanisms as most advantageous for low-copy plasmid fitnessDOI 10.1101/2025.02.11.637630Read

Why do plasmids manipulate the expression of bacterial phenotypes?Semantic proximity Read

Emerging patterns of plasmid-host coevolution that stabilize antibiotic resistanceSemantic proximity Read

Plasmids promote antimicrobial resistance through Insertion Sequence-mediated gene inactivationSemantic proximity Read

Positive Selection Inhibits Plasmid Coexistence in Bacterial Genomes.Semantic proximity Read

Evolutionary mechanisms that determine which bacterial genes are carried on plasmidsSemantic proximity Read

Variability of plasmid fitness effects contributes to plasmid persistence in bacterial communities.Semantic proximity Read

The distribution of plasmid fitness effects explains plasmid persistence in bacterial communitiesSemantic proximity Read

CRISPR-Cas is beneficial in plasmid competition, but limited by competitor toxin-antitoxin activity when horizontally transferredSemantic proximity Read

Emerging patterns of plasmid-host coevolution that stabilize antibiotic resistance.Semantic proximity Read

Genomic Islands as minimal hitchers of conjugative elementsSemantic proximity Read

Interspecific competition can drive the loss of conjugative plasmids from a focal species in a microbial communitySemantic proximity Read

Exclusion Systems Preserve Host Cell Homeostasis and fitness, Ensuring Successful Dissemination of Conjugative Plasmids and Associated Resistance GenesSemantic proximity Read