Article

Exclusion Systems Preserve Host Cell Homeostasis and fitness, Ensuring Successful Dissemination of Conjugative Plasmids and Associated Resistance Genes

2025-04-19

Abstract excerpt

<h4>ABSTRACT</h4> Plasmid conjugation is a major driver of antibiotic resistance dissemination in bacteria. In addition to genes required for transfer and maintenance, conjugative plasmids encode exclusion systems that prevent host cells from acquiring identical or redundant plasmids. Despite their ubiquity, the biological impact of these systems remains poorly understood. Here, we investigate the importance of t...

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Literature Corpus work: 6969dc75-e5f2-5cdb-b945-829264d37ec4
DOI: 10.1101/2025.04.18.649494

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