Article

Bacteriocin peer selection for the production of antibiotic selection free biotherapeutic pDNA

2023-10-23

Abstract excerpt

Plasmid vectors are well established tools used to genetically engineer bacteria both in the laboratory and at industrial scale. The past few decades have seen a rising interest in the use of plasmid DNA (pDNA) for biotherapeutic applications. This interest is a strong driver for the development of technologies to increase pDNA production at biopharmaceutical scale in terms of decreasing production costs and meeti...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 06e923a3-b10c-5505-bf1f-be393565b106
DOI: 10.1101/2023.10.23.563565

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Bacteriocin peer selection for the production of antibiotic selection free biotherapeutic pDNADOI 10.1101/2023.10.23.563565Read

miniVec: A miniaturized plasmid backbone supporting antibiotic-free and additive-free fermentation with enhanced yield and functionalitySemantic proximity Read

New Generation of Plasmid Backbones Devoid of Antibiotic Resistance Marker for Gene Therapy TrialsSemantic proximity Read

Use of Staby®technology for development and production of DNA vaccines free of antibiotic resistance geneSemantic proximity Read

Targeting multidrug-resistant bacteria with genetic-information-free protein-only phagesSemantic proximity Read

Plasmid-free cheater cells commonly evolve during laboratory growthSemantic proximity Read

Two new plasmid post-segregational killing mechanisms for the implementation of synthetic gene networks in <i>E. coli</i>Semantic proximity Read

Novel genetic modules encoding high-level antibiotic-free protein expression in probiotic lactobacilliSemantic proximity Read

Plasmid BiopharmaceuticalsSemantic proximity Read

Lactococcus lactis DPC5598, a plasmid-free derivative of a commercial starter, provides a valuable alternative host for culture improvement studies.Semantic proximity Read

Versatile allelic replacement and self-excising integrative vectors for plasmid genome mutation and complementation.Semantic proximity Read

Transfer of Plasmid DNA to Clinical Coagulase-Negative Staphylococcal Pathogens by Using a Unique BacteriophageSemantic proximity Read

Self-assembling T7 phage syringes with modular genomes for targeted delivery of penicillin against β-lactam-resistant Escherichia coliSemantic proximity Read