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Profiling the methylome targets of the histone lysine methyltransferase DOT1L

2017-01-01

Abstract excerpt

Research surrounding the epigenetic regulation of gene expression is gaining momentum, and deservedly so. There are many examples of disease states, including cancers, which are associated with aberrant epigenetic markers, including erroneous protein post-translational modifications (PTMs) of the histones of chromatin. A particularly attractive area of study is histone lysine methylation, as this is one of the mos...

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Literature Corpus work
9be0785f-baab-5701-b7b3-33d2dc75a327
DOI
10.25560/68063
Open publication

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