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Article

NFIB induces functional astrocytes from human pluripotent stem cell-derived neural precursor cells mimicking in vivo astrogliogenesis.

Journal of cellular physiology - 1 Nov 2021

Yeon Gyu-Bum, Shin Won-Ho, Yoo Seo Hyun, Kim Dongyun, Jeon Byeong-Min, Park Won-Ung, Bae Yeonju, Park Jae-Yong, You Seungkwon, Na Dokyun, Kim Dae-Sung

Abstract excerpt

The ability to generate astrocytes from human pluripotent stem cells (hPSCs) offers a promising cellular model to study the development and physiology of human astrocytes. The extant methods for generating functional astrocytes required long culture periods and there remained much ambiguity on whether such paradigms follow the innate developmental program. In this report, we provided an efficient and rapid method...

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Identifiers

PMID: 33949692
DOI: 10.1002/jcp.30405

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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