Article

Application of the immunoregulatory receptor LILRB1 as a novel crystallisation chaperone for class I peptide-MHC complexes

2017-11-02

Abstract excerpt

X-ray crystallographic studies of class I peptide-MHC molecules (pMHC) continue to provide important insights into immune recognition, however their success depends on generation of diffraction-quality crystals, which remains a significant challenge. While protein engineering techniques such as surface-entropy reduction and lysine methylation have proven utility in facilitating and/or improving protein crystallisa...

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Identifiers and source

Literature Corpus work: 9b4ab776-d3bc-5669-b604-1ffb58bc3ee7
DOI: 10.1101/213207

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