Article

CXCR4 blockade alleviates pulmonary and cardiac outcomes in early COPD

2023-03-10

Abstract excerpt

<h4>ABSTRACT</h4> Chronic obstructive pulmonary disease (COPD) is a prevalent respiratory disease lacking effective treatment. Focusing on early COPD should help to discover disease modifying therapies. We aimed to examine the role of the CXCL12/CXCR4 axis in early COPD from both human samples and murine models. Blood samples and lung tissues of early COPD patients and controls were obtained in order to analyse C...

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Literature Corpus work: 9b393876-2f79-507e-b059-10e52d633891
DOI: 10.1101/2023.03.10.529743

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