Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

CC chemokine receptor 5 and CXC chemokine receptor 6 expression by lung CD8+ cells correlates with chronic obstructive pulmonary disease severity.

The American journal of pathology - 1 Sept 2007

Freeman Christine M, Curtis Jeffrey L, Chensue Stephen W

Abstract excerpt

Chronic obstructive pulmonary disease (COPD) is a progressive disease associated with a cellular inflammatory response. CD8(+) T cells are implicated in COPD pathogenesis, and their numbers significantly correlate with the degree of airflow limitation. Dendritic cells (DCs) are important sentinel immune cells, but little is known about their role in initiating and maintaining the CD8 T-cell response in COPD. To...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antigens, CD1
Share to CD83 Antigen

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Chemokine CCL3

Share to Chemokines, CXC

Share to Receptors, Chemokine

Share to Receptors, CXCR3

Share to Receptors, Scavenger

Share to Receptors, Virus

Source

Open in PubMed Open full text

Identifiers

PMID: 17640964
DOI: 10.2353/ajpath.2007.061177
PMCID: PMC1959492

Genes

CCR5
CXCR6
CCL3
CXCL16
CXCL9
CXCR3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

CC chemokine receptor 5 and CXC chemokine receptor 6 expression by lung CD8+ cells correlates with chronic obstructive pulmonary disease severity.PMID 17640964Read ↗

The CXCR6/CXCL16 axis links inflamm-aging to disease severity in COVID-19 patientsSemantic proximity Read ↗

Inflammatory mechanisms in patients with chronic obstructive pulmonary disease.Semantic proximity Read ↗

Gender differences in the T-cell profiles of the airways in COPD patients associated with clinical phenotypes.Semantic proximity Read ↗

Inflammatory phenotype drives different immunosuppressive response in COPD exacerbations.Semantic proximity Read ↗

Identification of Siglec-1-negative alveolar macrophages with proinflammatory phenotypes in chronic obstructive pulmonary disease.Semantic proximity Read ↗

Impact of smoking on dendritic cell phenotypes in the airway lumen of patients with COPD.Semantic proximity Read ↗

A CEACAM6-High Airway Neutrophil Phenotype and CEACAM6-High Epithelial Cells Are Features of Severe Asthma.Semantic proximity Read ↗

Biomarkers in chronic obstructive pulmonary disease.Semantic proximity Read ↗

CXCR4 blockade alleviates pulmonary and cardiac outcomes in early COPDSemantic proximity Read ↗

Th17 profile in COPD exacerbations.Semantic proximity Read ↗

Sputum SLC40A1 as a Novel Biomarker is Increased in Patients with Acute Exacerbation of Chronic Obstructive Pulmonary DiseaseSemantic proximity Read ↗

Low CC16 mRNA Expression Levels in Bronchial Epithelial Cells Are Associated with Asthma SeveritySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.