Article
A Regulatory Role of Chemokine Receptor CXCR3 in the Pathogenesis of Chronic Obstructive Pulmonary Disease and Emphysema.
Inflammation - 1 Jun 2021
Li Lun, Liu Yi, Chiu Chin, Jin Yang, Zhou Weixun, Peng Min, Chen Lung-Chi, Sun Qinghua, Gao Jinming
Abstract excerpt
Chronic obstructive pulmonary disease (COPD)/pulmonary emphysema is driven by the dysregulated airway inflammation and primarily influenced by the interaction between cigarette smoking (CS) and the individual's susceptibility. The inflammation in COPD involves both innate and adaptive immunity. By binding to its specific ligands, chemokine receptor CXCR3 plays an important role in regulating tissue inflammation...
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