Article

Differential Activity of MAPK signalling Defines Fibroblast Subtypes in Pancreatic Cancer

2023-11-01

Abstract excerpt

<h4>ABSTRACT</h4> Fibroblast heterogeneity is increasingly recognised across cancer conditions. Given their important contribution to disease progression, mapping out fibroblasts’ heterogeneity is critical to devise effective anti-cancer therapies. Cancer-associated fibroblasts (CAFs) represent the most abundant cell population in pancreatic ductal adenocarcinoma (PDAC). Whether CAF phenotypes are differently spe...

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Literature Corpus work: 9b365856-c220-563d-938a-be06f20777cb
DOI: 10.1101/2023.10.30.564752

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