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Titan cells formation in <i>Cryptococcus neoformans</i> is finely tuned by environmental conditions and modulated by positive and negative genetic regulators

2017-09-20

Abstract excerpt

The pathogenic fungus Cryptococcus neoformans exhibits morphological changes in cell size during lung infection, producing both typical size 5 to 7 µm cells and large titan cells (> 10 µm and up to 100 µm). We found and optimized in vitro conditions that produce titan cells in order to identify the ancestry of titan cells, the environmental determinants, and the key gene regulators of titan cell formation. Titan...

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Literature Corpus work
9cd0fa9a-f820-5c9d-85a8-de98ff6f171e
DOI
10.1101/191668
Open publication

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Titan cells formation in <i>Cryptococcus neoformans</i> is finely tuned by environmental conditions and modulated by positive and negative genetic regulatorsDOI 10.1101/191668
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