Article

Dynamic genome plasticity during unisexual reproduction in the human fungal pathogen <i>Cryptococcus deneoformans</i>

2021-06-01

Abstract excerpt

Genome copy number variation occurs during each mitotic and meiotic cycle and it is crucial for organisms to maintain their natural ploidy. Defects in ploidy transitions can lead to chromosome instability, which is a hallmark of cancer. Ploidy in the haploid human fungal pathogen Cryptococcus neoformans is exquisitely orchestrated and ranges from haploid to polyploid during sexual development and under various en...

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Literature Corpus work: ace5c21a-07bb-5461-9465-9260577ca5a4
DOI: 10.1101/2021.06.01.446667

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