Article

The Cryptococcus neoformans Titan Cell: From In Vivo Phenomenon to In Vitro Model

2018-09-14

Abstract excerpt

During infection, the human fungal pathogen Cryptococcus neoformans undergoes an unusual change in size, from small haploid yeast to large polyploid Titan cells. This transition is now well recognized as a virulence factor, but significant questions remain about how Titanisation is regulated and how it influences disease progression. Progress has been impeded by the lack of an in vitro model for the yeast-to-Titan...

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Literature Corpus work: 017be2e1-d5be-562c-899d-d3d23bde5845
DOI: 10.1007/s40588-018-0107-9

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