Article

ERp44 is Required for Endocardial Cushion Development by Regulating VEGFA Secretion in Myocardium

2021-07-03

Abstract excerpt

Rationale: Endocardial cushions are precursors of the valvoseptal complex that separates the four heart chambers and control blood flow through the heart. Abnormalities in endocardial cushion development lead to atrioventricular septal defects (AVSDs), which affect 1 in 2,100 live births. Several genes have been implicated in the development of endocardial cushions. Specifically, endoplasmic reticulum-resident pro...

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Literature Corpus work: 9ad03208-6232-5d44-8e51-c5dde339502f
DOI: 10.1101/2021.07.02.450976

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