Article
Endoplasmic reticulum resident protein 44 (ERp44) deficiency in mice and zebrafish leads to cardiac developmental and functional defects.
Journal of the American Heart Association - 20 Oct 2014
Wang Ding-Yan, Abbasi Cynthia, El-Rass Suzan, Li Jamie Yuanjun, Dawood Fayez, Naito Kotaro, Sharma Parveen, Bousette Nicolas, Singh Shalini, Backx Peter H, Cox Brian, Wen Xiao-Yan, Liu Peter P, Gramolini Anthony O
Abstract excerpt
BACKGROUND: Endoplasmic reticulum (ER) resident protein 44 (ERp44) is a member of the protein disulfide isomerase family, is induced during ER stress, and may be involved in regulating Ca(2+) homeostasis. However, the role of ERp44 in cardiac development and function is unknown. The aim of this study was to investigate the role of ERp44 in cardiac development and function in mice, zebrafish, and embryonic stem...
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