Mixed effects models for quantitative trait loci mapping with inbred strains.

Abstract excerpt

Fixed effects models have dominated the statistical analysis of genetic crosses between inbred strains. In spite of their popularity, the traditional models ignore polygenic background and must be tailored to each specific cross. We reexamine the role of random effect models in gene mapping with inbred strains. The biggest difficulty in implementing random effect models is the lack of a coherent way of...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Breeding
• Share to Chromosome Mapping
• Share to Computational Biology