Article

Alkali hydrolysis of recombinant proteins allows for the rapid identification of class I MHC-restricted CTL epitopes.

1993-10-01

Abstract excerpt

Abstract The characterization of the epitopes recognized by CTL provides insights into the nature of protective immune responses and facilitates the development of methods to enhance immunity to human pathogens. However, no easily applicable approach for CTL epitope identification has been developed. We present a rapid and efficient method for locating CTL epitopes within a protein. The gene encoding the protein o...

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Literature Corpus work: 9ab6f7fb-803d-5a94-ab14-7ec5762e71b4
DOI: 10.4049/jimmunol.151.8.3971

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