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Article

Expression of a membrane protease enhances presentation of endogenous antigens to MHC class I-restricted T lymphocytes.

Cell - 11 Dec 1992

Eisenlohr L C, Bacik I, Bennink J R, Bernstein K, Yewdell J W

Abstract excerpt

We find that expression of the membrane dipeptidyl carboxypeptidase angiotensin-converting enzyme (ACE) enhances presentation of certain endogenously synthesized peptides to major histocompatibility complex (MHC) class I-restricted cytotoxic T lymphocytes. ACE appears to function only in an intracellular secretory compartment of antigen-presenting cells. ACE-enhanced antigen presentation requires the expression...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 1333889
DOI: 10.1016/0092-8674(92)90392-p

Genes

ACE
TAP1
TAP2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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