Article
Identification of the major late human cytomegalovirus matrix protein pp65 as a target antigen for CD8<sup>+</sup> virus‐specific cytotoxic T lymphocytes
1 May 1994
Abstract excerpt
Primary cytomegalovirus (CMV) infection and reactivation of persistent CMV are associated with significant morbidity and mortality in immunocompromised individuals. Although recovery from CMV disease is correlated with the development of CMV-specific cytotoxic T lymphocytes (CTL), the major viral target antigens to which the response is directed are ill-defined, though they may comprise viral structural elements....
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