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Article

Cytomegalovirus selectively blocks antigen processing and presentation of its immediate-early gene product.

Nature - 24 Oct 1996

Gilbert M J, Riddell S R, Plachter B, Greenberg P D

Abstract excerpt

Recognition of virus-infected cells by CD8+ cytotoxic T lymphocytes requires that the viral proteins be processed into peptides, the derived peptides transported into the endoplasmic reticulum and inserted into the binding groove of a major histocompatibility complex class I molecule, and the antigenic complex exported to the cell surface. However, viral pathogens can disrupt this process and interfere with...

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Identifiers

PMID: 8878482
DOI: 10.1038/383720a0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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