Article

Quantifying signal persistence in the T cell signaling network using an optically controllable antigen receptor

2020-10-30

Abstract excerpt

<h4>SUMMARY</h4> T cells discriminate between healthy and infected cells with remarkable sensitivity when mounting an immune response. It has been hypothesized that this efficient detection requires combining signals from discrete antigen-presenting cell interactions into a more potent response, requiring T cells to maintain a ‘memory’ of previous encounters. To quantify the magnitude of this phenomenon, we have...

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Literature Corpus work: 9a959bbd-193e-59b2-8f21-b9b53923bad8
DOI: 10.1101/2020.10.30.362194

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