Article
Antigen Receptor Nanoclusters: Small Units with Big Functions.
Trends in immunology - 1 Oct 2016
Liu Wanli, Wang Haopeng, Xu Chenqi
Abstract excerpt
Adaptive lymphocytes express highly variable antigen receptors, allowing them to recognize a large variety of proteins, for example, derived from pathogens and tumor cells. Despite decades of investigations, the signaling mechanisms of these receptors are still incompletely understood. Super-resolution imaging studies revealed that antigen receptors, their coreceptors, and even some downstream signaling molecules...
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