Article

Mycobacterial infection induces a specific human innate immune response

2015-04-03

Abstract excerpt

The innate immune system provides the first response to pathogen infection and orchestrates the activation of the adaptive immune system. Though a large component of the innate immune response is common to all infections, pathogen-specific responses have been documented as well. The innate immune response is thought to be especially critical for fighting infection with Mycobacterium tuberculosis (MTB), the causat...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 05f6473b-093b-5a2b-8643-4ea150ec9f54
DOI: 10.1101/017483

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Mycobacterial infection induces a specific human innate immune responseDOI 10.1101/017483Read

Mycobacterial infection induces a specific human innate immune response.Semantic proximity Read

Mycobacterium tuberculosis, macrophages, and the innate immune response: does common variation matter?Semantic proximity Read

Integrative and comparative genomic analyses of mammalian macrophage responses to intracellular mycobacterial pathogensSemantic proximity Read

Innate Immune Defenses in Human Tuberculosis: An Overview of the Interactions between Mycobacterium tuberculosis and Innate Immune Cells.Semantic proximity Read

An Interferon-Related Signature in the Transcriptional Core Response of Human Macrophages to Mycobacterium tuberculosis InfectionSemantic proximity Read

Integrative Genomics of the Mammalian Alveolar Macrophage Response to Intracellular MycobacteriaSemantic proximity Read

Mycobacterium tuberculosis: An Adaptable Pathogen Associated With Multiple Human DiseasesSemantic proximity Read

Integrative Analysis of Human Macrophage Inflammatory Response Related to Mycobacterium tuberculosis VirulenceSemantic proximity Read

Comparative transcriptomics reveals common and strain-specific responses of human macrophages to infection with Mycobacterium tuberculosis and Mycobacterium bovis BCGSemantic proximity Read

Single-cell transcriptome sequencing reveals altered peripheral blood immune cells in patients with severe tuberculosisSemantic proximity Read

Human alveolar macrophage response to Mycobacterium tuberculosis: immune characteristics underlying large inter-individual variabilitySemantic proximity Read

Beyond the Clinic: The Activation of Diverse Cellular and Humoral Factors Shapes the Immunological Status of Patients with Active TuberculosisSemantic proximity Read