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Human Alveolar and Monocyte-Derived Human Macrophage Responses to Mycobacterium tuberculosis

5 Jun 2024

Abstract excerpt

Alveolar macrophages (AMs) and recruited monocyte-derived macrophages (MDMs) mediate early lung immune responses to Mycobacterium tuberculosis. Differences in the response of these distinct cell types are poorly understood and may provide insight into mechanisms of tuberculosis pathogenesis. The objective of this study was to determine whether M. tuberculosis induces unique and essential antimicrobial pathways in...

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PMID: 38836816
DOI: 10.4049/jimmunol.2300885

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