Article
Apamin inhibits renal interstitial inflammation and fibrosis via suppressing TGF-β1 and STAT3 signaling pathway in vivo and in vitro
2020-11-16
Abstract excerpt
<title>Abstract</title> <p><bold>Background </bold>Renal fibrosis is a progressive and chronic process that influences kidneys with chronic kidney disease (CKD), irrespective of cause, leading to irreversible failure of renal function and end-stage kidney disease. Among the signaling related to renal fibrosis, transforming growth factor-β1 (TGF-β1) signaling is a major pathway that induces the activation of myofi...
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Identifiers and source
- Literature Corpus work
- 9a8d1ad5-00e6-5f0f-ae1c-b5fb80cf274e
- DOI
- 10.21203/rs.3.rs-108119/v1