Article
Renal interstitial fibrosis: mechanisms and evaluation.
Current opinion in nephrology and hypertension - 1 May 2012
Farris Alton B, Colvin Robert B
Abstract excerpt
PURPOSE OF REVIEW: Tubulointerstitial injury in the kidney is complex, involving a number of independent and overlapping cellular and molecular pathways, with renal interstitial fibrosis and tubular atrophy (IFTA) as the final common pathway. Furthermore, there are multiple ways to assess IFTA. RECENT FINDINGS: Cells involved include tubular epithelial cells, fibroblasts, fibrocytes, myofibroblasts,...
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