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Article

TGF-Beta as a Master Regulator of Diabetic Nephropathy

23 Jul 2021

Abstract excerpt

Diabetic nephropathy (DN) is one of the most common complications in diabetes mellitus and the leading cause of end-stage renal disease. TGF-β is a pleiotropic cytokine and has been recognized as a key mediator of DN. However, anti-TGF-β treatment for DN remains controversial due to the diverse role of TGF-β1 in DN. Thus, understanding the regulatory role and mechanisms of TGF-β in the pathogenesis of DN is the...

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Chronic Kidney Disease and Diabetes
Renal and related cancers
TGF-β signaling in diseases

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 34360646
DOI: 10.3390/ijms22157881

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