Article

Landscape of immune-related signatures induced by targeting of different epigenetic regulators in melanoma: implications for immunotherapy.

2022-08-08

Abstract excerpt

<title>Abstract</title> <p>Background. Improvement of efficacy of immune checkpoint blockade (ICB) remains a major clinical goal. Association of ICB with immunomodulatory epigenetic drugs is an option. However, epigenetic inhibitors show a heterogeneous landscape of activities. Analysis of transcriptional programs induced in neoplastic cells by distinct classes of epigenetic drugs may foster identification of th...

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Literature Corpus work: 9a856040-bcec-5618-af9f-d5632cdcd070
DOI: 10.21203/rs.3.rs-1918233/v1

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