Article

Landscape of immune-related signatures induced by targeting of different epigenetic regulators in melanoma: implications for immunotherapy

2022-04-14

Abstract excerpt

<h4>Background</h4> Innovative cancer immunotherapy approaches aim at combining immune checkpoint inhibitors with other immunomodulatory agents. Epigenetic regulators can control immune-related genes, therefore targeting them with specific inhibitors may be a potential way forward. Here we identified immune-related signatures induced by four classes of epigenetic drugs in human melanoma cells to define the most p...

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Literature Corpus work: 5988fcc1-e967-595f-8a9e-f38b7a2e0320
DOI: 10.1101/2022.04.13.488140

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