Article

Improved Tumor-Type informed compared to Tumor-Informed Mutation Tracking for ctDNA Detection and Microscopic Residual Disease Assessment in Epithelial Ovarian Cancer

2025-03-11

Abstract excerpt

<title>Abstract</title> <p>Background Epithelial ovarian cancer (EOC) is a leading cause of cancer mortality in women, often diagnosed at advanced stages. While first-line treatments improve survival, relapses remain common, with 5-year survival rates below 40%. Circulating tumor DNA (ctDNA) is a promising biomarker for non-invasive EOC detection and monitoring. It may help assess treatment response, notably mic...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 9a7a4215-bc59-5738-99a1-5c05d1d87f00
DOI: 10.21203/rs.3.rs-6031886/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Improved Tumor-Type informed compared to Tumor-Informed Mutation Tracking for ctDNA Detection and Microscopic Residual Disease Assessment in Epithelial Ovarian CancerDOI 10.21203/rs.3.rs-6031886/v1Read

Sensitive and specific multi-cancer detection and localization using methylation signatures in cell-free DNASemantic proximity Read

Detection of ovarian cancer using plasma cell-free DNA methylomesSemantic proximity Read

TruSight Oncology 500: Enabling Comprehensive Genomic Profiling and Biomarker Reporting with Targeted SequencingSemantic proximity Read

Improved circulating tumor DNA profiling by simultaneous extraction of DNA methylation and copy number information from Methylated DNA Sequencing data (MeD-seq)Semantic proximity Read

A Sensitive and Transparent Method for Tumor-Informed Detection of Circulating Tumor DNA in Ovarian Cancer Using Whole-Genome Sequencing.Semantic proximity Read

Targeted methylation sequencing of plasma cell-free DNA for cancer detection and classificationSemantic proximity Read

Molecular residual disease detection in resected, muscle-invasive urothelial cancer with a tissue-based comprehensive genomic profiling–informed personalized monitoring assaySemantic proximity Read

Molecular analysis for ovarian cancer detection in patient-friendly samplesSemantic proximity Read

Precision oncology based on omics data: The NCT Heidelberg experienceSemantic proximity Read

Knowledge-informed multimodal cfDNA analysis improves sensitivity and generalization in cancer detectionSemantic proximity Read

The potential of circulating tumor DNA methylation analysis for the early detection and management of ovarian cancerSemantic proximity Read

Serial Circulating Tumor DNA Analysis with a Tumor-Naïve Next-Generation Sequencing Panel Detects Minimal Residual Disease and Predicts Outcome in Ovarian Cancer.Semantic proximity Read