Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A Sensitive and Transparent Method for Tumor-Informed Detection of Circulating Tumor DNA in Ovarian Cancer Using Whole-Genome Sequencing.

International journal of molecular sciences - 12 Dec 2024

Thusgaard Christine Fribert, Sadegh Sepideh, Jochumsen Kirsten Marie, Kruse Torben Arvid, Thomassen Mads

Abstract excerpt

Circulating tumor DNA (ctDNA) is a biomarker that could potentially improve the survival rate of ovarian cancer (OC), e.g., by monitoring treatment response and early relapse detection. However, an optimal method for ctDNA analysis in OC remains to be established. We developed a method for tumor-informed single-nucleotide variant detection of ctDNA in OC using whole-genome sequencing. Tumor and plasma samples...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged
Share to Biomarkers, Tumor

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Circulating Tumor DNA

Share to High-Throughput Nucleotide Sequencing

Share to Ovarian Neoplasms

Share to Polymorphism, Single Nucleotide

Share to Whole Genome Sequencing

Source

Identifiers

PMID: 39769113
DOI: 10.3390/ijms252413349

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A Sensitive and Transparent Method for Tumor-Informed Detection of Circulating Tumor DNA in Ovarian Cancer Using Whole-Genome Sequencing.PMID 39769113Read ↗

Advances in application of circulating tumor DNA in ovarian cancer.Semantic proximity Read ↗

Early and accurate detection of ovarian cancer by profiling cell-free mitochondrial DNA fragmentomics in multi-ethnic populationSemantic proximity Read ↗

Circulating cell-free DNA and circulating tumor cells, the "liquid biopsies" in ovarian cancer.Semantic proximity Read ↗

Circulating tumor DNA: a noninvasive biomarker for tracking ovarian cancerSemantic proximity Read ↗

Current Applications and Challenges of Next-Generation Sequencing in Plasma Circulating Tumour DNA of Ovarian CancerSemantic proximity Read ↗

A novel circulating miRNA panel for non-invasive ovarian cancer diagnosis and prognosisSemantic proximity Read ↗

Integrative analysis of cfDNA features from ultra-low coverage whole genome sequencing enables robust detection of ovarian cancerSemantic proximity Read ↗

Can circulating cell free DNA be a promising marker in ovarian cancer? – a genome-scale profiling study in a single institutionSemantic proximity Read ↗

Circulating Cell-Free DNA or Circulating Tumor DNA in the Management of Ovarian and Endometrial CancerSemantic proximity Read ↗

Can circulating tumor DNA be used for direct and early stage cancer detection?Semantic proximity Read ↗

Improved Tumor-Type informed compared to Tumor-Informed Mutation Tracking for ctDNA Detection and Microscopic Residual Disease Assessment in Epithelial Ovarian CancerSemantic proximity Read ↗

Diagnostic significance assessment of the circulating cell-free DNA in ovarian cancer: An updated meta-analysisSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.