Article

JAK1/2 Inhibition Delays Cachexia and Improves Survival through Increased Food Intake

2025-10-22

Abstract excerpt

Lung cancer is the leading cause of cancer-related death and is frequently accompanied by reduced food intake and cachexia, a debilitating syndrome characterized by weight loss and skeletal muscle wasting. We sought to identify contributors to cachexia using a murine model of lung cancer that reproduces key features of this syndrome. A multiplex cytokine screening approach, integrated with western blot and transcr...

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Identifiers and source

Literature Corpus work: 9a68c436-4431-5bfe-8495-42a095e083a8
DOI: 10.1101/2025.10.21.683287

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