Article

Optimized dCas9 Programmable Transcriptional Activators for Plants

2022-06-10

Abstract excerpt

Understanding how gene expression impacts plant development and physiology is important for rationally engineering improved crops. Programmable Transcriptional Activators (PTAs), including CRISPR-Cas activators, have traditionally relied on a limited number of transcriptional activation domains. Usually the VP64 domain, derived from human herpes simplex virus, is fused to a DNA-binding domain to activate target ge...

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Literature Corpus work: 9a5d485d-0dfe-5558-94b7-268b29423b77
DOI: 10.1101/2022.06.10.495638

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