Article

Targeting dCas9-SunTag to a susceptibility gene promoter is sufficient for CRISPR interference

2025-03-13

Abstract excerpt

Cassava production in sub-Saharan Africa is severely impacted by diseases. Most pathogens require interaction with host susceptibility factors to complete their life cycles and cause disease. Targeted DNA methylation is an epigenetic strategy to alter gene expression in plants and we previously reported that a zinc-finger fused to DMS3 could establish methylation at the promoter of MeSWEET10a , a bacterial suscep...

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Identifiers and source

Literature Corpus work: 305cafbc-cfda-5c3e-a6db-0e74ca9d98a3
DOI: 10.1101/2025.03.11.642632

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