Article

SCLC_CellMiner: Integrated Genomics and Therapeutics Predictors of Small Cell Lung Cancer Cell Lines based on their genomic signatures

2020-03-09

Abstract excerpt

<h4>Summary</h4> Model systems are necessary to understand the biology of SCLC and develop new therapies against this recalcitrant disease. Here we provide the first online resource, CellMiner-SCLC ( https://discover.nci.nih.gov/SclcCellMinerCDB ) incorporating 118 individual SCLC cell lines and extensive omics and drug sensitivity datasets, including high resolution methylome performed for the purpose of the cu...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 9a421c17-9ab3-5ea8-9a5f-da62ebfe4b00
DOI: 10.1101/2020.03.09.980623

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

SCLC_CellMiner: Integrated Genomics and Therapeutics Predictors of Small Cell Lung Cancer Cell Lines based on their genomic signaturesDOI 10.1101/2020.03.09.980623Read

SCLC-CellMiner: A Resource for Small Cell Lung Cancer Cell Line Genomics and Pharmacology Based on Genomic SignaturesSemantic proximity Read

Single cell profiling reveals novel tumor and myeloid subpopulations in small cell lung cancerSemantic proximity Read

Molecular Subtypes and Targeted Therapeutic Strategies in Small Cell Lung Cancer: Advances, Challenges, and Future PerspectivesSemantic proximity Read

Integrative analysis of multi-omics data reveals the heterogeneity and signatures of immune therapy for small cell lung cancerSemantic proximity Read

SCLC TumorMiner: A Genomics Platform for Small Cell Lung Cancer Precision OncologySemantic proximity Read

Genomic and transcriptomic analysis of a library of small cell lung cancer patient-derived xenograftsSemantic proximity Read

Signatures of plasticity, metastasis, and immunosuppression in an atlas of human small cell lung cancerSemantic proximity Read

Expression patterns and prognostic relevance of subtype‐specific transcription factors in surgically resected small‐cell lung cancer: an international multicenter studySemantic proximity Read

High-resolution lung adenocarcinoma expression subtypes identify tumors with dependencies on <i>MET, CDK4, CDK6</i> , and <i>PD-L1</i>Semantic proximity Read

In‐depth proteomic analysis reveals unique subtype‐specific signatures in human small‐cell lung cancerSemantic proximity Read

Molecular phenotypes stratify small cell lung cancer for targeted therapy and immunotherapy.Semantic proximity Read

Spatial multi-omics unveils the monoclonal origin, neuroendocrine plasticity, and microenvironment niches in combined small cell lung cancerSemantic proximity Read