Article

CHIP is associated with cardiovascular disease in the UK Biobank

2023-11-30

Abstract excerpt

Clonal hematopoiesis (CH) is a form of age-related somatic mosaicism. CH encompasses both clonal events with recognizable leukemic driver mutations, such as CH of indeterminate potential (CHIP) and mosaic chromosomal alterations (mCAs), as well as clonal states without clear driver mutations. Stacey et al . identify cases of CH from whole genome sequencing (WGS) data in a subset of 130,709 UK Biobank (UKB) partici...

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Literature Corpus work: 9a27533c-4543-5e6b-a4c8-89ba770484f4
DOI: 10.1101/2023.11.30.23299001

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