Article

DYRK1A regulates the recruitment of 53BP1 to the sites of DNA damage in part through interaction with RNF169

2018-05-21

Abstract excerpt

<h4>Summary</h4> Human DYRK1A gene encoding Dual-specificity tyrosine (Y)- Regulated Kinase 1A (DYRK1A) is a dosage-dependent gene whereby either trisomy or haploinsufficiency result in developmental abnormalities. However, the function and regulation of this important protein kinase are not fully understood. Here we report proteomic analysis of DYRK1A in human cells that revealed a novel role of DYRK1A in the D...

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Literature Corpus work: 9a108693-9ddb-5069-bc42-ba98dcd81a12
DOI: 10.1101/327510

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