Article

βTrCP is involved in the localization of the MRN complex on chromatin to enhance DNA damage repair

2025-03-06

Abstract excerpt

<h4>ABSTRACT</h4> Genomic instability underlies various diseases, including cancer. This instability arises from defects in critical cellular processes, particularly those involved in DNA damage repair. Therefore, a detailed understanding of these repair mechanisms is essential for developing strategies to prevent or diagnose such diseases. The MRN complex, composed of MRE11, NBS1, and RAD50, is among the earlies...

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Literature Corpus work: 9d41e582-4dd9-5136-a36b-3a5efdc71185
DOI: 10.1101/2025.03.06.640826

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