Article

CCR2+TREM-1+ monocytes promote Natural killer T cell dysfunction contributing towards HBV disease progression

2024-03-26

Abstract excerpt

Natural killer T (NKT) cells are amongst the most important innate immune cells against Hepatitis B virus (HBV) infection. Moreover, previous studies have shown that HBV infection induced TREM-1 + expression in monocyte and secretion of inflammatory cytokines. Thus, this prompted us to elucidate the role of TREM-1 + monocytes in regulating the function of NKT cells. Ninety patients and 20 healthy participants were...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 99ee8c49-a5b9-5be6-815c-ebe8a8a721c2
DOI: 10.21203/rs.3.rs-4024517/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

CCR2+TREM-1+ monocytes promote Natural killer T cell dysfunction contributing towards HBV disease progressionDOI 10.21203/rs.3.rs-4024517/v1Read

HBV and HBsAg strongly reshape the phenotype, function, and metabolism of DCs according to patients' clinical stage.Semantic proximity Read

Identification of a distinct NK-like hepatic T-cell population activated by NKG2C in a TCR-independent mannerSemantic proximity Read

CD38+HLA-DR+CD8+ T Cells induced by IL-15 exert liver injury through NKG2D in chronic hepatitis B cirrhosisSemantic proximity Read

Macrophage Phenotypes and Hepatitis B Virus InfectionSemantic proximity Read

Blocking of monocyte-associated B7-H1 (CD274) enhances HCV-specific T cell immunity in chronic hepatitis C infection.Semantic proximity Read

Single-cell multimodal analysis reveals the dynamic immunopathogenesis of HBV-ACLF progressionSemantic proximity Read

TREM1 <sup>+</sup> regulatory myeloid cells expand in steatohepatitis-HCC and associate with poor prognosis and therapeutic resistance to immune checkpoint blockadeSemantic proximity Read

Myeloid cell path to malignancy: insights into liver cancerSemantic proximity Read

Monocytic MDSCs homing to thymus contribute to age-related CD8+ T cell tolerance of HBVSemantic proximity Read

A Programmed Cell Death-1 Haplotype is Associated with Clearance of Hepatitis B Virus.Semantic proximity Read

Recent advances in different interactions between toll-like receptors and hepatitis B infection: a reviewSemantic proximity Read

Function and autophagy of monocyte-derived dendritic cells is affected by hepatitis B virus infectionSemantic proximity Read