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Article

Blocking of monocyte-associated B7-H1 (CD274) enhances HCV-specific T cell immunity in chronic hepatitis C infection.

Journal of leukocyte biology - 1 Mar 2008

Jeong Hye-Young, Lee Youn-Jae, Seo Su-Kil, Lee Soo-Woong, Park Sung-Jae, Lee Jeong-Nyeo, Sohn Hae-Sook, Yao Sheng, Chen Lieping, Choi Inhak

Abstract excerpt

The establishment of a chronic hepatitis C (CHC) infection is associated with defective HCV-specific T cell responses. Recent studies suggest that negative T cell regulators such as programmed death 1 (PD-1) contribute to the impairment of virus-specific T cell functions in chronic viral infections. However, the implication of peripheral monocytes from CHC patients in the inhibition of HCV-specific T cell...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 18086898
DOI: 10.1189/jlb.0307168

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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