Article

Multi-sample, multi-platform isoform quantification using empirical Bayes

2025-02-08

Abstract excerpt

Accurate quantification of RNA isoform abundance is crucial for understanding gene regulation, cellular behavior, and disease mechanisms. While short-read (SR) sequencing provides high-throughput and cost-effective transcript quantification, it suffers from read-to-transcript ambiguity. Long-read (LR) sequencing reduces this ambiguity but faces challenges such as high error rates, biases, and lower throughput. Exi...

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Literature Corpus work: 99d1ab30-fe5f-51a2-8916-4fa1d4b85e16
DOI: 10.1101/2025.02.08.637184

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