Article

Context-Aware Transcript Quantification from Long Read RNA-Seq data with Bambu

2022-11-16

Abstract excerpt

Most approaches to transcript quantification rely on fixed reference annotations. However, the transcriptome is dynamic, and depending on the context, such static annotations contain inactive isoforms for some genes while they are incomplete for others. To address this, we have developed Bambu, a method that performs machine-learning based transcript discovery to enable quantification specific to the context of in...

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Literature Corpus work: 1d29e00f-4daf-5d6c-af22-5bb153444962
DOI: 10.1101/2022.11.14.516358

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