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Article

Phase-separating enzyme-responsive condensates for inhalable delivery of biomacromolecules

2025-06-23

Abstract excerpt

Inhaled delivery of biomacromolecules shows extensive promise for treating a large variety of diseases, especially pulmonary and respiratory diseases. Although nanoparticle-based vehicles enhance intracellular uptake efficiency, it still remains challenging for biomacromolecules inhaled delivery to overcome cytotoxicity, cargo leakage and off-target effect. Here, we present an enzyme-responsive condensates based h...

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Identifiers and source

Literature Corpus work
99c79895-1bb4-5306-9b92-2ac53d19af21
DOI
10.1101/2025.06.17.660252
Open publication

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Phase-separating enzyme-responsive condensates for inhalable delivery of biomacromoleculesDOI 10.1101/2025.06.17.660252
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