Article

Rapid generation of circulating and mucosal decoy ACE2 using mRNA nanotherapeutics for the potential treatment of SARS-CoV-2

2020-07-25

Abstract excerpt

<h4>ABSTRACT</h4> Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) enters through the airways and infects the lungs, causing lethal pulmonary damage in vulnerable patients. This virus contains spike proteins on its envelope that binds to human angiotensin-converting enzyme 2 (hACE2) expressed on the surface of airway cells, enabling entry of the virus for causing infection 1,2 . In severe cases, the...

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Literature Corpus work: 866dbfaa-9151-5f17-b811-972f4e65f7dd
DOI: 10.1101/2020.07.24.205583

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