Article

The NS1 protein of influenza B virus binds 5’-triphosphorylated dsRNA to suppress RIG-I activation and the host antiviral response

2024-02-01

Abstract excerpt

<title>Abstract</title> <p>Influenza A and B viruses overcome the host antiviral response to cause a contagious and often severe human respiratory disease. Here, integrative structural biology and biochemistry studies on non-structural protein 1 of influenza B virus (NS1B) reveal a previously unrecognized viral mechanism for innate immune evasion. Conserved basic groups of its C-terminal domain (NS1B-CTD) bind 5’...

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Literature Corpus work: 99af2b30-9e3a-51c8-b422-c6ec51e9fdd3
DOI: 10.21203/rs.3.rs-3874434/v1

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