Article
Interactions between the Influenza A Virus RNA Polymerase Components and Retinoic Acid-Inducible Gene I
19 Jun 2014
Abstract excerpt
UNLABELLED: The influenza A virus genome possesses eight negative-strand RNA segments in the form of viral ribonucleoprotein particles (vRNPs) in association with the three viral RNA polymerase subunits (PB2, PB1, and PA) and the nucleoprotein (NP). Through interactions with multiple host factors, the RNP subunits play vital roles in replication, host adaptation, interspecies transmission, and pathogenicity. In...
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