Article

Irradiation and lithium treatment alter the global DNA methylation pattern and gene expression underlying a shift from gliogenesis towards neurogenesis in human neural progenitors

2023-03-21

Abstract excerpt

<title>Abstract</title> <p>Central nervous system (CNS) tumors account for almost a third of pediatric cancers and are the largest contributor to cancer-related death in children. Cranial radiation therapy (CRT) is, often in combination with chemotherapy and surgery, effective in the treatment of high-grade childhood brain cancers, but it has been associated with late complications in 50–90% of survivors, such as...

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Literature Corpus work: 99a95e71-480c-59ff-8514-ea7127218ed2
DOI: 10.21203/rs.3.rs-2679270/v1

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