Article

Human iPSC-derived neural stem cells display a radial glia-like signature <i>in vitro</i> and favorable long-term safety in transplanted mice

2023-08-04

Abstract excerpt

<h4>ABSTRACT</h4> Human induced pluripotent stem cell-derived neural stem/progenitor cells (hiPSC-NSCs) are a promising source for cell therapy approaches to treat neurodegenerative and demyelinating disorders. Despite ongoing efforts to characterize hiPSC-derived cells in vitro and in vivo , we lack comprehensive genome- and transcriptome-wide studies addressing hiPSC-NSC identity and safety, which are critica...

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Literature Corpus work: 8ca0910e-1b56-533e-827f-82fe4e5c9b13
DOI: 10.1101/2023.08.04.551937

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