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Article

Sirt1 regulates glial progenitor proliferation and regeneration in white matter after neonatal brain injury

19 Dec 2016

Abstract excerpt

Regenerative processes in brain pathologies require the production of distinct neural cell populations from endogenous progenitor cells. We have previously demonstrated that oligodendrocyte progenitor cell (OPC) proliferation is crucial for oligodendrocyte (OL) regeneration in a mouse model of neonatal hypoxia (HX) that reproduces diffuse white matter injury (DWMI) of premature infants. Here we identify the...

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PMID: 27991597
DOI: 10.1038/ncomms13866

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