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Article

Small-Molecule-Based Lineage Reprogramming Creates Functional Astrocytes.

Cell reports - 19 Jul 2016

Tian E, Sun Guoqiang, Sun Guihua, Chao Jianfei, Ye Peng, Warden Charles, Riggs Arthur D, Shi Yanhong

Abstract excerpt

Growing evidence indicates important roles for astrocytes in neurodevelopment and diseases. However, astrocytes and their roles in these processes remain poorly understood. Despite recent progress in reprogramming somatic cells into different types of neural cells, reprogramming to astrocytes has lagged. Here, we show that functional astrocytes can be generated from mammalian fibroblasts using only small...

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Identifiers

PMID: 27396343
DOI: 10.1016/j.celrep.2016.06.042
PMCID: PMC9228989

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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